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Céline Robiou Du Pont

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Open access Aug 2026

A novel stilbene derivative targets RAD51 activity and sensitizes DU145 prostate cancer cells to cisplatin.

Homologous recombination (HR) is a high-fidelity DNA repair pathway responsible for the resolution of double-strand breaks, with the RAD51 recombinase playing a pivotal role through the formation of nucleoprotein filaments on single-stranded DNA. Overexpression of RAD51 is frequently observed in cancer cells, where it...

Lucie Fonteneau, H. Benhelli-Mokrani, Céline Robiou Du Pont et al. · 0 citations

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