Author

Chad M. Aldridge

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Open access Aug 2026

Genomic insights into stroke recovery: cross-phenotype associations

Abstract Stroke is a major cause of long-term disability with variable recovery. While clinical factors such as initial severity play a role, genetic factors are increasingly recognized as important contributors to stroke recovery. Genotype studies are generally focused on a single post-stroke behavioural domain, but s...

Chad M. Aldridge, R. Braun, L. Parodi et al. · Brain Communications · 0 citations

Open access Sep 2026

Evaluation of functional annotation-informed and ancestry-specific polygenic risk scores for ischemic stroke

Functional annotation-informed PRSs and expanded reference panels modestly improved prediction, particularly among EA participants, and limited performance among AA participants underscores the need for larger, more diverse genomic datasets and integrative models incorporating genetic, clinical, lifestyle, and social d...

N. Armstrong, V. Srinivasasainagendra, Amit Patki et al. · Frontiers in Bioinformatics · 0 citations