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Author

Chaithanya Sudha Pd

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Open access Sep 2026

A QUALITY BY DESIGN APPROACH FOR THE DEVELOPMENT AND VALIDATION OF A REVERSE-PHASE ULTRA-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR SIMULTANEOUS ESTIMATION OF ACEBROPHYLLINE AND N–ACETYLCYSTEINE IN BULK AND PHARMACEUTICAL DOSAGE FORM

Objectives: The aim of this study was to develop and validate an accurate, fast, and reliable stability-indicating reverse-phase ultra-performance liquid chromatography (RP–UPLC) technique based on quality by design (QbD) for acebrophylline (ACB) and N–acetylcysteine (NAC) simultaneously in pure and tablet formulation....

Jerom Md, Ranganath Mk, Chaithanya Sudha Pd · 0 citations
Open access Aug 2026

QUALITY BY DESIGN-DRIVEN REVERSED PHASE-HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD DEVELOPMENT, OPTIMIZATION, AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF SOFOSBUVIR AND VELPATASVIR IN BULK AND TABLET DOSAGE FORM

Objective: To create and validate a stability-indicating Reversed Phase-High Performance Liquid Chromatography(RP-HPLC) technique based on Quality by Design (QbD) for the simultaneous measurement of Sofosbuvir (SOF) and Velpatasvir (VEL) in pharmaceutical dosage forms and bulk. Methods: A QbD approach using Central Com...

J. R, Chaithanya Sudha Pd, Chenchu Lakshmi Knv · 0 citations

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