This study is the first to identify circRNA0857 as a critical regulator in NDV infection, elucidating its role in enhancing NDV-induced autophagy via the miR1709/ATG3 and miR1746/ATG7 signaling axes.
Siyuan Wang, Yang Qu, Weiwei Liu et al.· Journal of Virology· 0 citations
Newcastle disease virus (NDV), a significant avian paramyxovirus, depends on the acquisition of host-derived membranes for viral envelope assembly during budding. However, the relationship between NDV budding efficiency and host metabolic reprogramming remains incompletely understood. Our previous research demonstrated...
Jun Dai, Fan-Xin Liu, Yiyi Feng et al.· Poultry Science· 0 citations
The PLpro-TM protein is identified as a pan-coronavirus antagonist of nucleocytoplasmic trafficking and innate immune response and established PLpro-TM-mediated cleavage of Importin α1 as a conserved immune evasion strategy across coronaviruses and highlights this interaction as a potential target for broad-spectrum an...
Jie-Huang Wang, Wenxiang Xue, Ying-Jie Sun et al.· bioRxiv· 0 citations
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