Chancie Chou

Development of Niclosamide Prodrugs Preserves Wnt Inhibition and Anticancer Activity Through Rapid Bioactivation

Colorectal, lung, breast, and melanoma malignancies remain major contributors to cancer-related morbidity and mortality worldwide, underscoring the need for therapeutic strategies that can be rapidly translated to the clinic. Drug repurposing offers an attractive route for accelerating oncology drug development, partic...