Author

Chang-Chun Zhou

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Sep 2026

A cascade-release microsphere-engineered injectable hydrogel enables immune remodeling and sustained chondrogenesis for facial cartilage regeneration.

Structural facial cartilage regeneration is impeded by limited intrinsic repair and injury-driven inflammatory remodeling, which promote fibrosis, matrix degradation, and phenotypic instability. Here, we report a temporally programmed immuno-chondrogenic hydrogel system that combines mesenchymal stem cells (MSCs) with...

Jing-Ting Huang, Si-Jie Li, Xi-Hao Wang et al. · Journal of materials chemist... · 0 citations

Aug 2026

Ultrasound-Programmable ROS-Responsive Hydrogel Orchestrates Staged Immunomodulation and Neurorepair after Intracerebral Hemorrhage.

Intracerebral hemorrhage (ICH) remains a highly lethal and disabling subtype of stroke, and the lack of effective disease-modifying therapies largely reflects the complexity of its secondary injury mechanisms: oxidative stress predominates early and fuels neuroinflammation, whereas impaired neurorepair persists into th...

Ruiying Han, Yun-Sen He, Yong-Lin He et al. · ACS Applied Materials and In... · 0 citations

Aug 2026

An Adhesive Multifunctional Hydrogel for Sequential Anti-inflammatory, Antioxidant, and Pro-regenerative Diabetic Wound Therapy.

A multifunctional hydrogel dressing was constructed from carboxymethyl chitosan and oxidized dextran as the dynamic network, incorporating CeO2 nanozymes for early anti-inflammatory and antioxidant effects and PLGA microspheres loaded with astragaloside IV for sustained pro-regeneration.

Xi-Hao Wang, Jing-Ting Huang, Chuipin Kong et al. · ACS Applied Materials and In... · 0 citations