Author

Chang-Fa Tang

2 papers indexed here

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Open access Sep 2026

Hypoxic Exercise Alleviates Diabetic Skeletal Myopathy in Zebrafish in Association with Hif1a/Foxo3a Signaling and Mitochondrial Quality Control

Type 2 diabetes mellitus (T2DM) is characterized by skeletal muscle insulin resistance, which contributes to systemic metabolic dysregulation and diabetic myopathy (DM), a complication involving the loss of muscle mass and contractile function. Although hypoxic exercise has demonstrated metabolic benefits in chronic di...

Hao-Ming Li, Zhang-Ling Chen, Qin-Hua Deng et al. · International Journal of Mol... · 0 citations

Open access Aug 2026

Activation of the Nrf2-ARE Signaling Pathway Mediates the Neuroprotective Effects of Exercise in a Mouse Model of Chronic Parkinson’s Disease

Clear pharmacological evidence is provided that the neuroprotective effect of regular treadmill exercise against chronic PD strictly depends on the Nrf2-ARE pathway, indicating that Nrf2 is a key mechanistic node linking exercise and neuroprotection.

Shu-Wei Zhang, Dong Yang, Chang-Fa Tang et al. · International Journal of Mol... · 0 citations