Chang-Feng Huang

Targeting the secretory autophagy–extracellular vesicle interface: fate decisions and translational opportunities

Autophagy preserves cellular homeostasis through lysosomal degradation, but its machinery also participates in extracellular release. This creates a pharmacological problem: changing autophagy or extracellular vesicle (EV) output can alter intracellular disposal, inflammatory signaling and communication between cells i...