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Chang-Fu Li

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Open access Oct 2026

Metabolic Engineering of Yarrowia lipolytica for De Novo Biosynthesis of Umbelliferone

Umbelliferone, a key precursor for the biosynthesis of high-value furanocoumarin derivatives, is produced via the shikimate pathway. The oleaginous yeast Yarrowia lipolytica possesses an inherently robust shikimate pathway; however, de novo biosynthesis of umbelliferone in this microbial chassis has not been realized t...

Feng-Liu Lu, Ying Luo, Zhen-Ming Lei et al. · 0 citations

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