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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Chang-Jiang Du

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Review Open access Sep 2026

Radiotherapy for overcoming immune checkpoint inhibitor resistance in esophageal squamous cell carcinoma

Immunotherapy has improved outcomes for patients with esophageal squamous cell carcinoma (ESCC), yet a substantial proportion develop resistance. The tumor microenvironment (TME) drives this resistance through four hallmarks: physical barriers formed by cancer-associated fibroblast (CAF)-deposited extracellular matrix...

Chang-Jiang Du, Yuan-Fei Li · 0 citations

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