Open access
Jul 2026
AI-driven multi-omics deciphering of extrachromosomal circular DNA rescues hidden targets in colorectal cancer.
BACKGROUND Extrachromosomal circular DNA (eccDNA) is an emerging tumor biomarker notable for its tumor-specific amplification and contribution to genomic heterogeneity. However, the substantial heterogeneity of eccDNAs poses a significant challenge for characterization. Current identification tools rely predominantly o...
Lili Zhang, Jian Cui, Tianhan Sun et al.
· Cell communication and signa... · 0 citations