Bifidobacterium animalis subsp. lactis V9 overcomes CYFRA 21-1–linked immunochemotherapy resistance in NSCLC via microbial metabolites
Gut dysbiosis drives therapeutic resistance, yet the relationships among typical tumor markers, gut microbiota, and treatment efficacy remain poorly defined. Here, elevated serum CYFRA 21-1 in advanced non–small cell lung cancer (NSCLC) correlates with gut dysbiosis, including Bifidobacterium animalis depletion and red...