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Author

Changmin Wang

2 papers indexed here

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Open access Oct 2026

PPAR-γ/SGK1/GSK3β/Nrf2 signaling pathway contributes to the neuroprotective effects of lycopene in depressed mice.

INTRODUCTION Major depressive disorder (MDD) is a neuropsychiatric disorder associated with abnormal neuronal activity in specific brain regions. Recent evidence suggests that oxidative stress- and neuroinflammation-driven impairments in synaptic structure and neuronal function may contribute to depression, yet the pre...

Yong-Si Zhao, Meng-Ni Chang, Cheng-Xin Hu et al. · 0 citations
Open access Jul 2026

The Wnt signaling regulator Dkk3 improves neural-activity homeostasis to prevent stress-induced anxiety disorder.

OBJECTIVES The medial prefrontal cortex (mPFC) is a cortical brain region that involved in various emotional disorder. Neuroinflammation and oxidative stress are reported to associated with the pathogenesis of anxiety, but the underlying brain mechanisms remain unclear. METHODS AND RESULTS Here, using a mouse model o...

Xiao Chen, Ruojing Guo, Changmin Wang et al. · 0 citations

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