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Chang-Shun Chen

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Review Open access Sep 2026

Integrin αVβ3 as a context-dependent regulator of bone homeostasis: Insights into osteoporosis pathogenesis and therapeutic targeting (Review)

Osteoporosis (OP) is a multifactorial skeletal disorder characterized by progressive bone loss, microarchitectural deterioration and an increased risk of fragility fractures resulting from disrupted bone remodeling. Integrin αVβ3 functions as an important regulator of bone homeostasis by coordinating bone cell-extracel...

Chang-Shun Chen, Xing-Xi Hu, Si-Xing Wei et al. · 0 citations

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