Open access
Jan 2026
rs2357322 and rs17726078 Contribute to Breast Cancer Risk by Regulating DLX2 Expression
Recursion of the segment containing these two SNPs by CRISPR/Cas9 can significantly increase DLX2 mRNA and protein expression, cell proliferation, colony formation, migration, and wound healing, thus suggesting that the cis‐regulatory element is an attenuator for gene expression.
Xin-Xin Zhang, Hao Guo, Hai-Yan Li et al.
· The Breast Journal · 0 citations