Author

Chang-Ung Kim

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Open access Jul 2026

Capless self-amplifying mRNA vaccine induces dose-sparing protective immunity against HPAI clade 2.3.4.4 H5 virus in mice.

Findings support CLsamRNA as a distinct cap-independent RNA vaccine platform with dose-sparing protective efficacy against HPAI H5 viruses and supportatic optimization of key genetic elements enhanced antigen expression from the CLsamRNA backbone.

Beom Kyu Kim, Ji-Hyun Park, Won-Suk Choi et al. · Molecular Therapy · 1 citation