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Chang-Wei Wei

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Open access Jul 2026

Octameric dGTPase assemblies mediate broad anti-phage defense

Deoxyguanosine triphosphatases (dGTPases) are nucleotide-depleting enzymes known to play a role in antiviral defense. While their enzymatic mechanism is established, the structural and functional diversity of dGTPases remains poorly understood. Here, we report a systematic analysis of dGTPase homologs across bacteria,...

Miao Shi, Peipei Li, Quanjin Li et al. · 0 citations

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