Benzo[a]pyrene-induced METTL3 overexpression accelerates renal cell carcinoma progression via m6A modification of LTB4R mRNA and enhanced Treg infiltration.
Benzo[a]pyrene (BaP) is a widespread environmental pollutant and a representative polycyclic aromatic hydrocarbon with well-established carcinogenic properties. However, the molecular mechanisms through which BaP promotes renal cell carcinoma (RCC) progression, particularly those involving epigenetic modifications and...