Chang-Xue Liu

Development and validation of a machine learning-based model for predicting survival in patients with bladder neuroendocrine carcinoma: a large retrospective study

Bladder neuroendocrine carcinoma (BNEC) is a rare yet highly aggressive malignancy with an extremely poor prognosis. The current TNM staging system provides limited prognostic information and validated prognostic prediction tools are lacking. This study aimed to develop and validate a machine learning (ML)-based mo...

Development and validation of a machine learning-based model for predicting survival in patients with bladder neuroendocrine carcinoma: a large retrospective study

Integrating network pharmacology and molecular simulations to identify Doconexent-associated regulatory networks in renal cell carcinoma

Renal cell carcinoma (RCC) is increasingly recognized as being influenced by gut microbiota-associated metabolites, although the underlying regulatory mechanisms remain unclear. In this study, an integrated network pharmacology framework was applied to systematically investigate the role of microbial metabolites in R...