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Chang-Yi Cui

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Open access Jul 2026

Reduced LANCL1-AS1 in old human skeletal muscle diminishes mitochondrial activity, shortens mt-mRNA poly(A) tails, and suppresses myogenesis

It is proposed that the age-associated reduction in LANCL1-AS1 contributes to impaired mitochondrial function and reduced myogenic capacity in aging skeletal muscle.

Jen-Hao Yang, Elizabeth K. Izydore, K. Mazan-Mamczarz et al. · bioRxiv · 0 citations