Integrative Network Toxicology and Experimental Validation Define Mechanisms of Perfluorodecanoic Acid (PFDA) Induced Granulosa Cell Toxicity and Attenuation by Kaempferol in HGrC1 Cells.
Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants increasingly linked to female reproductive toxicity. Among them, perfluorodecanoic acid (PFDA) has been implicated in ovarian dysfunction, yet the molecular basis of its ovotoxicity remains insufficiently defined. Here, we investigated...