Open access
Jul 2026
Association of APOBEC mutagenesis with stromal and endothelial niche remodeling and PCDH9-linked signaling alterations in colorectal cancer
This multi-omics study identifies APOBEC activity as a central orchestrator of CRC evolution, associated with stromal-vascular remodeling and intracellular oncogenic activation through PCDH9-associated signaling alterations.
Junting Chen, Jiaming Cao, Baosen Zhou et al.
· Frontiers in Immunology · 0 citations