Sep 2026
Melatonin ameliorates manganese-induced neurological deficits in mice by inhibiting TXNIP signaling-mediated neuroinflammation and microglial pyroptosis: Role of SIRT6.
Findings suggest that Mel mitigates Mn-associated hippocampal neuroinflammatory injury by partially restoring SIRT6-mediated epigenetic repression of Txnip and reducing TXNIP/NLRP3-driven microglial pyroptosis.
Jia Liu, Ji-Xing Liang, Ke-Yu Chen et al.
· Journal of Hazardous Materia... · 0 citations