BACKGROUND
Dysregulated lipid metabolism and chemoresistance are key drivers of breast cancer progression. Lectin, mannose-binding 2 (LMAN2) is frequently overexpressed in human breast tumors and functions as an oncogenic driver. However, whether LMAN2 contributes to chemoresistance remains unknown.
METHODS
We integr...
Changjiao Yan, Fengqiang Cui, Chutuo Liu et al.· Breast Cancer Research· 0 citations
Abstract Background Thyroid cancer incidence is rising worldwide, yet comprehensive longitudinal data linking contemporary demographic, pathological, and surgical trends to recurrence risk remain scarce. Methods A retrospective analysis was performed on 9504 thyroid cancer patients from 2008 to 2023. Based on the year...
Sijin Guo, Yang Wang, Changjiao Yan et al.· Journal of the Endocrine Soc...· 0 citations
BACKGROUND
m5C modification plays a vital role in the progression of human cancers, including breast cancer (BC), but the function of NOP2/Sun RNA methyltransferase 2 (NSUN2), an RNA m5C modification enzyme, remains largely unclear.
METHODS
qRT-PCR, western blot and IHC assays were carried out to determine the expres...
Xin Li, Changjiao Yan, Jun Yi et al.· Cell Division· 0 citations
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