Sex-Dependent Placental Neuroendocrine Disruption by Maternal Arsenic Exposure: From Neurotransmitter Dysregulation to Neurobehavioral Outcomes.
Epidemiological evidence suggests that developmental arsenic (As) exposure increases behavioral abnormalities in offspring. However, how placental neuroendocrine function and sex-specific responses contribute to these effects remains poorly understood. Here, we demonstrate that maternal As exposure induces trophoblasti...