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Changwen Xu

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Open access Aug 2026

Functional characterization of the Est-type macrolide esterase ECO-1 from Escherichia coli

Macrolides are widely used in both human and veterinary medicine, and enzymatic inactivation represents an important yet underexplored resistance mechanism beyond the well-studied Ere family. Here, we functionally characterized ECO-1, an Est-type macrolide esterase identified from Escherichia coli . Phylogenetic...

Tao Song, Xin-Yu Ye, Ya-Ni He et al. · 0 citations

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