Open access
Oct 2026
Dipeptidyl Peptidase-4 Inhibitor Enhances the Efficacy of Docetaxel via Adenosine Triphosphate Depletion and Modulation of Mitochondrial Fusion-Fission in Castration-Resistant Prostate Cancer.
PURPOSE Dipeptidyl peptidase-4 (DPP4) inhibitors may influence prostate cancer (PCa) progression and clinical outcomes. Therefore, here we investigated whether the DPP4 inhibitor sitagliptin could enhance the cytotoxic effect of docetaxel (DOC) in castrationresistant prostate cancer cells and the underlying metabolic a...
W. Lee, Seong Cheol Kim, J. Yoon et al.
· The World Journal of Men's H... · 0 citations