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Author

Chao Chen

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Open access Aug 2026

Lithocholic Acid Ameliorates Diabetic Nephropathy by Suppressing the AGEs/RAGE Signaling Pathway and Modulating Inflammation, Endoplasmic Reticulum Stress, and Lipid Metabolism

Diabetic nephropathy (DN) is a leading cause of end-stage renal disease, and the advanced glycation end products (AGEs) and their receptor RAGE play a critical pathogenic role in DN progression. This study investigated the therapeutic mechanisms of licochalcone A (LCA), a bioactive flavonoid from licorice, against...

Lupeng Wang, Ying Ni, Pan-Pan Han et al. · 0 citations
Open access Aug 2026

Impaired antioxidant defense associated with flavonoid biosynthesis reprogramming in the mangrove Acanthus ilicifolius under high salinity

Findings show that A. ilicifolius compensates for impaired antioxidant defenses by redirecting metabolism toward flavonoid synthesis, providing novel insights into the molecular basis of mangrove salt tolerance and its potential medicinal applications.

Qing-Fan Xiong, Zhengzheng Sun, Lin Su et al. · 0 citations

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