Implications of pentose phosphate metabolism and astrocyte co-expression patterns in the pathogenesis of Alzheimer’s disease: evidence from artificial intelligence-driven omics and clinical validation
A novel PA-associated molecular axis in AD is revealed, with HDAC3 serving as a central epigenetic-metabolic regulator within astrocytes and being identified as a potential therapeutic target for AD.
Chao Gong
· Frontiers in Neuroscience · 0 citations