Author

Chao Xing

2 papers indexed here

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Open access Oct 2026

Female sex accelerates retinal neurodegeneration in Herc3-deficient mice

Retinal degeneration involves mechanisms common to other neurodegenerative diseases, including mitochondrial dysfunction, inflammation, and impaired proteostasis via the ubiquitin-proteasome system (UPS). Although sex hormones modulate these pathways, the molecular basis of this sexual dimorphism remains poorly...

Dogan Can Kirman, Ashley A. Rowe, Ashwani Kumar et al. · Biology of Sex Differences · 0 citations

Open access Jul 2026

A mutation in Bicdl1 (BICD family-like cargo adaptor 1) leads to mild outer retina thinning and late retinal dysfunction in a mouse model.

Despite the expression of many cargo adaptor proteins and dynein activators in the retina, a novel non-redundant role of Bicdl1 in retinal homeostasis is identified.

Gizem Ulker-Yilmazer, Dogan Can Kirman, Tian Yu et al. · Molecular Vision · 0 citations