Author

Chao Yang

3 papers indexed here

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Sep 2026

DNA Tetrahedral Nanoprobes-Based Logic-Gated FRET Sensor for in Situ Analysis of Dual MicroRNAs in Extracellular Vesicles

Conventional analysis of extracellular vesicle (EV)-derived microRNAs relies on vesicle lysis and RNA extraction, which disrupt native vesicular structure and eliminate intravesicular molecular cargoes. Here, we report a rigid DNA tetrahedral nanoprobes-based logic-gated Förster resonance energy transfer (FRET) plat...

Fang-Zhou Lan, Guang-Jin Tian, Ai-Peng Chen et al. · Analytical Chemistry · 0 citations

Aug 2026

Sensitive and Reproducible SERS Profiling of Tumor-Derived EVs via Uniform Microfluidic Nanobowl Arrays for Pancreatic Cancer Management.

Tumor-derived extracellular vesicles (EVs) are promising liquid biopsy biomarkers, yet their clinical translation is hindered by the trade-off between enhancement and reproducibility of SERS-based detection. Here, we present a microfluidic SERS platform integrating plasmonic nanobowl arrays that simultaneously achieve...

Ruoke Wang, Ai-Peng Chen, Yu-Qing Wang et al. · Nano letters (Print) · 0 citations

Sep 2026

Precise Mutation Detection in Low-Abundance Tumor-Derived Extracellular Vesicles via Microfluidic Immunomagnetic Reversible Affinity Capture

The MIRACLE platform is developed, an integrated system combining microfluidic magneto-controllable reversible affinity capture with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) for efficient, multiplexed detection of tumor-derived EV DNA mutations.

Xing Xu, Shan-Shan Liang, Heng-Kai Chen et al. · Analytical Chemistry · 0 citations