Open access
Jul 2026
NAcLat-DBS reduces GABAB expression of dopamine neurons to correct depressive symptoms in CMS mice
Findings identify a previously unrecognized role of GABAB in mediating the antidepressant outcome of NAcLat-DBS and suggest that modulation of the DA GABAB1 in VTA-NAcLat pathway could represent a pharmacological target for treatment-resistant depression.
Jia-Ni Jing, Chao Yuan, Xia Li et al.
· Neurotherapeutics · 1 citation