Intratracheal delivery of perfluorocarbon nanoparticles (PFCE NPs) enables 19F-MRI imaging of lung cancer via alveolar macrophage-mediated transport
Early and specific imaging of lung cancer remains a major clinical challenge. Here we report that intratracheal delivery of perfluoro-15-crown-5-ether nanoparticles (PFCE NPs, ~200 nm) enables persistent, high-contrast ¹⁹F magnetic resonance imaging (MRI) of orthotopic lung tumors through alveolar macrophage (AM)-media...