Chaoyi Yang

A DNA-based nanosensor for in situ precise imaging of lysosomal potassium ions via pH activation.

For subcellular imaging, activating probes by specific species in targeted organelles is an attractive strategy to eliminate nonspecific signals during transport. The characteristic pH (∼4.5-5.0) of lysosomes enables selective probe activation within lysosomes. In this work, a pH-activated K+ nanosensor for lysosomal K...