Preadolescent Morphine Exposure Produces Sexually Dimorphic Alterations in Adult Rat Spinal Nociceptive Processing.
Opioids are widely used for paediatric pain management; however, the long-term impacts of opioid exposure during later stages of neural development on spinal nociceptive circuitry remain unclear. We investigated whether repeated morphine exposure during preadolescence produces alterations in dorsal horn (DH) responses...