Open access
Aug 2026
Retinal degeneration in a mouse model of CRB1 disease rescued by the photoreceptor-specific CRB1-B isoform
Many genes involved in inherited diseases produce alternate mRNA isoforms that remain poorly characterized. Functional assessment of these isoforms could therefore unlock new insights into disease pathobiology or treatment. Here we investigated the function of the newly discovered “B” isoform of CRB1, a gene implicated...
Ekta Dembla, Juan C. Valdez-Lopez, Christopher Kozlowski et al.
· bioRxiv · 0 citations