Open access
Aug 2026
ZCCHC4 promotes replication-dependent histone mRNA translation through interaction with the eIF3 complex
This study establishes a previously unrecognized role for ZCCHC4 in histone synthesis, at least in part through its interaction with eIF3, thereby sustaining histone supply during S phase in tumor cells and point to a potential role for ZCCHC4 in tumorigenesis.
Ruiqi Wang, Xiaoyan Shi, Yang-Yi Zhang et al.
· Cell Death Discovery · 0 citations