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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Chen-Chen Tang

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Open access Oct 2026

Cross-species single-nucleus transcriptomics identifies microglial Arhgap22 as a conserved modulator of synaptic phagocytosis and depression-related behaviors

Microglia-regulated neuroinflammation is associated with major depressive disorder (MDD), yet the molecular drivers of pathological microglia-neuron interactions remain poorly defined. Here, we conducted single-nucleus RNA sequencing (snRNA-seq) of the prefrontal cortex (PFC) in mice susceptible to chronic social def...

Rui-Min Tian, Hong-Zhou Zuo, Chen-Chen Tang et al. · 0 citations

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