Chen Chongtham

Molecular histomorphometry and the emerging role of transcriptomics in celiac disease diagnosis and therapeutic trials

Abstract Background Celiac disease (CeD) is an autoimmune enteropathy in which diagnosis and disease monitoring rely on serology and small-intestinal histology. However, conventional histological assessment is semi-quantitative, subject to interobserver variability, and relatively insensitive to subtle mucosal changes,...