Review
Sep 2026
In vitro enzymatic synthesis of long-acting therapeutic proteins and peptides.
The site-specific functionalization of therapeutic proteins and peptides represents a significant challenge in modern synthetic chemistry due to the presence of numerous competing nucleophilic residues. Conventional chemical conjugation strategies not only suffer from poor regioselectivity-leading to high product heter...
Gao-Shuai Li, Yan-Lu Zhang, Qi-Cheng Zhu et al.
· Bioorganic chemistry (Print) · 0 citations