Open access
Sep 2026
Chrysin attenuates diabetes-induced retinal injury by inhibiting microglial GBP3/NLRP3/GSDMD-mediated pyroptosis.
BACKGROUND This study was designed to investigate whether chrysin, a natural flavone, alleviates experimental diabetic retinal disease and to define a microglia-centered mechanism involving guanylate-binding protein 3 (GBP3) and NLR family pyrin domain containing 3 (NLRP3)-gasdermin D (GSDMD) pyroptosis signaling. ME...
Qun Liu, Song-Min Wang, Xuan Chen et al.
· Animal Models and Experiment... · 0 citations