Review
Sep 2026
T-Cell Exhaustion and Senescence in Cancer: Regulatory Circuits and Therapeutic State Engineering.
This mechanistic view shifts the therapeutic question from how broadly to activate T cells to which states should be generated, preserved, or rescued and provides a testable basis for state-informed biomarker development and therapeutic design.
Jia-Shu Han, Xiaohong Lyu, Meng-Wei Wu et al.
· Cancer Letters · 0 citations