Chen Liu

GPR56 and CD319 identify distinct cytotoxic-associated DP and DN T-cell subsets in early systemic lupus erythematosus.

Peripheral CHOP+ CD4+ T-Cell Subsets Are Reduced and Clinically Relevant in Primary Sjögren's Syndrome.

OBJECTIVE Primary Sjögren's syndrome (pSS) is an autoimmune disease characterized by lymphocytic infiltration of exocrine glands and systemic immune dysregulation. Endoplasmic reticulum stress (ERS)-related transcription factor C/EBP homologous protein (CHOP) has been implicated in several autoimmune conditions, but it...

CD55 downregulation identifies a pathogenic CD4+ T cell axis linked to p38 MAPK signaling in rheumatoid arthritis.

CD4+ T cell dysfunction plays a critical role in the pathogenesis of rheumatoid arthritis (RA). In this study, we investigated the expression, phenotypic characteristics, and potential clinical significance of CD55, a membrane-bound complement regulatory protein, in peripheral blood CD4+ T cells from RA patients. Flow...