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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Chen-Qi Xu

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Aug 2026

Latent tumor killers awakened.

In this issue of Cancer Cell, Kehl et al. construct a single-cell atlas of bone marrow T cells from patients with bone marrow-resident malignancies, identifying tumor-reactive populations existing in a state of latent competence. A 15-gene signature identifies this subset, which is expanded by immunotherapies and predi...

Haochen Yang, Chen-Qi Xu · 0 citations
Open access Aug 2026

Spatial cholesterol homeostasis gatekeeps T-cell development and activation by orchestrating signaling and fitness

OSBP is identified as a central regulator of intracellular cholesterol transport that couples membrane cholesterol homeostasis to TCR signaling and ER integrity and is established as a fundamental metabolic determinant of thymocyte development and peripheral T-cell function.

Yanchi Li, Xing He, Chen-Xin Li et al. · 0 citations

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