Chen-Xi Wang

Phage-encoded protein PhiP targets HemA to block heme biosynthesis, suppressing bacterial growth and promoting phage propagation

ABSTRACT Bacteriophages encode diverse proteins that subvert host metabolism to promote viral propagation. Elucidating the functions and mechanisms of these proteins not only deepens our understanding of phage-host interactions but also offers new avenues for antibacterial development. Here, we identify PhiP, a protein...