Open access
Oct 2026
Integrated proteomic and metabolomic profiling characterizes tryptophan metabolic disturbance associated with mortality in ICU-admitted SFTS patients
Collectively, tryptophan metabolic disturbances coupled with inflammatory proteomic features may characterize fatal severe SFTS, and the identified metabolite–protein signatures may serve as promising prognostic biomarkers and potential therapeutic targets in critically ill patients.
Li Chen, Pu-Hui Liu, Chuan-Zhen Niu et al.
· Frontiers in Immunology · 0 citations