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Jul 2026

Development of an RPA-CRISPR/Cas12a-Based Assay for Sensitive and Visual Detection of Channel Catfish Calicivirus (ChCV).

Channel catfish calicivirus (ChCV) has emerged as a novel viral pathogen threatening the sustainability of channel catfish (Ictalurus punctatus) aquaculture. The absence of rapid, on-site detection methods has hindered effective disease prevention and control. In this study, a visual RPA-CRISPR/Cas12a detection platfor...

Chu Ma, Yong Zhou, Xin Ren et al. · 0 citations
Open access Aug 2026

Baicalin suppresses SVCV replication and is associated with modulation of the AMPK/mTOR-mediated autophagy pathway

Spring viremia of carp virus (SVCV) poses a major threat to carp aquaculture due to the lack of effective antiviral strategies. This study investigates the antiviral potential of baicalin in epithelioma papulosum cyprini (EPC) cells and zebrafish. Baicalin exhibits antiviral activity during both pretreatment and post-i...

Mingyang Xue, Mengwei Zhang, Yang Hu et al. · 0 citations
Open access Aug 2026

Type VII secretion system promotes Streptococcus agalactiae virulence through magnesium acquisition and capsule maintenance

Streptococcus agalactiae, also known as group B Streptococcus (GBS), is a major pathogen causing substantial economic losses in global tilapia aquaculture. The type VII secretion system (T7SS), present in Actinobacteria and Firmicutes, secretes effector proteins implicated in bacterial virulence, yet its functional mec...

Fengyan Li, Chen Xu, Weiyi Ma et al. · 0 citations

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