Author

Chen-Yan He

2 papers indexed here

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Preprint Oct 2026

Beyond the Transcriptome: Chromatin-Informed Prediction of Cell-State-Dependent Perturbation Responses

Predicting transcriptional responses to genetic perturbations is central to understanding gene function. Existing predictors primarily rely on transcriptomic measurements, although chromatin accessibility provides complementary information about the cellular context in which perturbations act. Using this information re...

Jia-Fa Ruan, Chen-Yan He, Rui-Jie Quan et al. · 0 citations

Open access Sep 2026

Amniotic-fluid metabolomics identifies phospholipid remodeling as a metabolic signature of intrauterine exposure in pregnancies with polycystic ovary syndrome

Amniotic fluid from pregnancies with polycystic ovary syndrome showed a distinct metabolic profile dominated by lipid remodeling, identifying phospholipid remodeling as a major amniotic-fluid metabolic signature of polycystic ovary syndrome-related intrauterine exposure.

Shi-Ming Wu, Jia-Yu Shi, Chen-Yan He et al. · Frontiers in Endocrinology · 0 citations