Author

Chen-Yu Yang

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Open access Sep 2026

Differential proteomic analysis of lung tissues in rats with high-altitude pulmonary edema and screening of potential biomarkers

Introduction High-altitude pulmonary edema (HAPE) is a severe complication of rapid exposure to high-altitude hypoxia, but its molecular mechanisms remain incompletely understood. This study aimed to characterize lung proteomic alterations in HAPE and identify candidate proteins associated with its pathophysiological p...

Dong-Mei Zhang, Ting-Ting Liu, Hong-Fang Mu et al. · Frontiers in Physiology · 0 citations

Aug 2026

XunZi, an AI biologist, reveals disease-modifying targets.

In Parkinson's disease (PD), where complex mechanisms and limited targets hamper therapy development, XunZi identifies aberrant activation of CHK2 and IRAK4 kinases across multiple models and establishes a paradigm-shifting framework to translate fragmented biomedical knowledge and data into actionable therapeutics.

Xinhe Huang, Junhong Qin, Fei Tang et al. · Nature Biomedical Engineerin... · 0 citations