Chen Zhang

Daphnetin Alleviates Sepsis-Associated Acute Kidney Injury by Promoting Autophagy and Suppressing Non-canonical NF-κB Signaling.

BACKGROUND Sepsis-Associated Acute Kidney Injury (SA-AKI) is a lifethreatening complication with high mortality and limited treatment options. Daphnetin (DAP), a coumarin derivative with anti-inflammatory activity, has shown promise in several inflammatory disorders, but its role in SA-AKI remains unclear. METHODS We...